In vitro synergistic interaction between amphotericin B and micafungin against Scedosporium spp.
نویسندگان
چکیده
The in vitro interaction between amphotericin B and micafungin against 36 isolates of Scedosporium spp. has been evaluated using checkerboard assays and the minimal effective concentration endpoint. Synergy was found for 82.4% of Scedosporium prolificans isolates and for 31.6% of Scedosporium apiospermum isolates. Antagonism was not observed.
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1. Greenberg RN, Mullane K, van Burik et al. Posaconazole as salvage therapy for zygomycosis. Antimicrob Agents Chemother 2006; 50: 126–33. 2. Dannaoui E, Afeltra J, Meis JFGM et al. In vitro susceptibilities of zygomycetes to combinations of antimicrobial agents. Antimicrob Agents Chemother 2002; 8: 2708–11. 3. Gómez-López A, Cuenca-Estrella M, Mellado E et al. In vitro evaluation of combinati...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 49 8 شماره
صفحات -
تاریخ انتشار 2005